Diethyl sulfate 硫酸二乙酯
CAS 64-67-5 MFCD00009099
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- {uni_hamburg} no charge; 1fragment
- {SNA} Alkyl Transfer, C-X Bond Formation (Non-Halogen), Chemical Synthesis, Synthetic Reagents
产品应用
- 有机合成。乙基化试剂。乙烯磺化作用的促进剂。
相关文献及参考
- Esterification of thermally unstable carboxylic acids, e.g. ß-keto acids, can be achieved in high yield in the presence of DBN (1,5-Diazabicyclo[4.3.0]non-5-ene, A13437): Synth. Commun., 6, 89 (1976).
- Short: II/27B
- Merck: 14,3130
- Merck: 14,3130 Beilstein:1,327
- Short: III/38B
- Short: II/5
安全信息
- R46 May cause inheritable genetic damage 可能引起遗传基因损害
- R45 May cause cancer 可能致癌
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
- R34 Causes burns 会导致灼伤
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
GHS Symbol
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H350 May cause cancer 可能致癌
- H340 May cause genetic defects 可能导致遗传性缺陷
- H302+H332
- H311 Toxic in contact with skin 皮肤接触中毒
- H332 Harmful if inhaled 吸入有害
- H302 Harmful if swallowed 吞食有害
- H312 Harmful in contact with skin 皮肤接触有害
- H302+H312+H332
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P305+P351+P338+P310
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P303+P361+P353+P310+P363
- P301+P330+P331+P310
- P303+P361+P353
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P305+P351+P338
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3700 mg/kg/81W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors REFERENCE : ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 74,241,1970
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 800 mg/kg/32W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application REFERENCE : ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 74,241,1970
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 85 mg/kg female 15 day(s) after conception TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Brain and Coverings - tumors REFERENCE : IARCCD IARC Scientific Publications. (Geneva, Switzerland) No.1-26, 1971-78. For publisher information, see IAPUDO. Volume(issue)/page/year: 4,45,1973
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 350 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 74,241,1970
TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 250 ppm/4H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,343,1949
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 600 uL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 12/30/1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 880 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,60,1949
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Ro
TYPE OF TEST : Micronucleu
TYPE OF TEST : DNA adduct TEST SYSTEM : Rodent - mouse Ascites tumor DOSE/DURATION : 5 umol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,95,1981
TYPE OF TEST : DNA damage TEST SYSTEM : Microorganism - not otherwise specified DOSE/DURATION : 9 gm/L REFERENCE : CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 2,363,1981
TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Human Lymphocyte DOSE/DURATION : 300 umol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 205,409,1988
TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 30 nmol/tube REFERENCE : PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 79,5971,1982
TYPE OF TEST : Dominant lethal test ROUTE OF EXPOSURE : Intraperitoneal TEST SYSTEM : Rodent - mouse DOSE/DURATION : 100 mg/kg/10W (Intermittent) REFERENCE : GNKAA5 Genetika (Moscow). For English translation, see SOGEBZ. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1965- Volume(issue)/page/year: 12(3),163,1976
TYPE OF TEST : Sex chromosome loss and nondisjunction RO
TYPE OF TEST : Host-m
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE : 340 mg/kg SEX/DURATION : female 15 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetal death REFERENCE : IARCCD IARC Scientific Publications. (Geneva, Switzerland) No.1-26, 1971-78. For publisher information, see IAPUDO. Volume(issue)/page/year: 4,45,1973
其他信息
- 储运特性:库房通风低温干燥; 与氧化剂、硝酸、食品添加剂分开存放
- Alfa Aesar:硫酸二乙酯,98% Diethyl sulfate, 98%(64-67-5)
- 毒性分级:中毒
- 下游产品:乙醚 --> 4-乙氧基苯基乙酸乙酯 --> 2-乙氧基苯甲酸 --> 禾草敌 --> N4-苯甲酰基胞嘧啶 --> 二乙二醇乙醚 --> 2-乙基巯基-4-氨基嘧啶-5-羧酸 --> 2-乙巯基-5-羟甲基-6-氨基嘧啶 --> 2-乙硫基-4-氨基嘧啶-5-羧酸乙酯 --> 乙氧基胺盐酸盐 --> 3-乙氧基苯酚 --> N-乙基咔唑 --> 对氯苯乙醚 --> 酸性橙116 --> 茵草敌 --> N,N-二乙基-邻甲基苯胺 --> 曲匹布通 --> 克罗米通 --> 柔软剂 QA --> 2-萘乙醚 --> 2-乙基乙酰乙酸乙酯
- 用途二:用于酚类的乙氧基化反应
- 有薄荷香。久贮色变深。能与乙醇和乙醚混溶,几乎不溶于水,水中溶解度:5 G/L (20°C)。在冷水中渐渐分解,在热水中迅速分解成乙醇及硫酸一乙酯,有刺激性,有致癌可能性。
- 外观性质:无色油状液体,略有醚的气味。
- 类别:有毒物品
- 硫酸二乙酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80049928 硫酸二乙酯;硫酸乙酯 500ml 47.6元 2011/04/16 D0525 硫酸二乙酯 Diethyl Sulfate 25ML 150元 2011/04/16 D0525 硫酸二乙酯 Diethyl Sulfate 500ML 240元
- Acros Organics:硫酸二乙酯 Diethyl sulfate, 99%(64-67-5)
- 灭火剂:泡沫、二氧化碳、砂土
- 用途三:硫酸二乙酯为反应性强的乙基化剂,广泛应用于染料、医药及其他精细化工产品的生产。还用于季铵盐的合成,用作脱水剂、挥发油抽提剂等。
- 用途四:有机合成。乙基化试剂。乙烯磺化作用的促进剂。
- 蒸气密度:5.3 (vs air)
- 蒸气压:<;0.01 mm Hg ( 20 °C)
- 可燃性危险特性:明火、高热可燃; 高热放出有毒硫氧化物气体; 与水、氧化剂反应
- Sigma Aldrich:64-67-5(sigmaaldrich)
- 上游原料:氯磺酸 --> 脱水剂
- 刺激数据:皮肤- 兔子 10 毫克/ 24小时 重度; 眼- 兔子 2 毫克 重度
- 职业标准:TWA 0.03 PPM (0.2 毫克/ 立方米)
- 用途一:用于医药、染料、香料、农药等,也用作乙基化试剂、乙烯磺化促进剂
- 方法一:有多种生产方法。1.由乙醇与硫酸反应而得。2.由乙醚与氯磺酸作用。3.将硫酸单乙酯加热或在脱水剂存在下蒸馏,可得硫酸二乙酯。4.乙烯与硫酸反应制得硫酸二乙酯。
- MSDS 信息:硫酸乙酯(64-67-5).msds
- MOL 文件:64-67-5.mol
- TCI Shanghai:硫酸二乙酯 Diethyl Sulfate,>;98.0%(GC)(64-67-5)
- 急性毒性:口服- 大鼠 LD50: 880 毫克/ 公斤; 口服- 小鼠 LD50: 647 毫克/ 公斤
- 图谱信息:硫酸二乙酯(64-67-5)红外图谱(IR1) 硫酸二乙酯(64-67-5)红外图谱(IR2)